Working collaboratively to provide creative solutions
to protein challenges in drug discovery
Fragment Screening by Crystallography: An Alternative to High Throughput Screening
We discuss the use of X-ray crystallography to perform fragment based drug discovery and present its application in a recent integrated Sygnature Discovery project.
Read the latest update from our Green Team, who recently improved the efficiency of our ultra-low temperature freezers and reduced their environmental impact
Sygnature Discovery is delighted to welcome Elise Ling to the Protein Science Team. Elise holds a PhD in Biochemistry and Structural Biology and enjoys cooking, running, and skiing.
Optimising a Crystal System for Fragment Screening
In this recent fragment screening case study, the key to success was establishing a robust crystal system.