Insights from Sygnature Discovery about protein supply, structure determination, mass spectrometry, and biophysical characterisation.
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Working collaboratively to provide creative solutions to protein  challenges in drug discovery

Advancing Biopharmaceutical Solutions

This month, we showcase two case studies demonstrating our expertise in biopharmaceutical development - from optimising production processes to characterising critical quality attributes.

Optimising Biopharmaceutical Production

This case study explores development of a robust production process, optimising construct design and downstream processing suitable for large-scale manufacture.

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Mass Spectrometry for Biopharmaceutical Quality

Learn how mass spectrometry was applied to elucidate critical quality attributes of a biotherapeutic protein, providing key insights into its structure, consistency, and overall integrity for drug development. Read more.

Early Validation of HTS Hits with X-ray Crystallography

Explore how X-ray crystallography enhances early validation of high-throughput screening hits, providing detailed structural insights to accelerate drug discovery. Read more.

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Rick Davies on Joining Sygnature

After two months as Director of Sygnature Protein Science and Structural Biology, Rick Davies shares insights on the transition, collaboration, and future opportunities.

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Protein Expression and Protein Purification

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Protein Structure Determination

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Protein
Characterisation
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Sygnature Discovery, BioCity, Pennyfoot Street, Nottingham, Nottinghamshire NG1 1GR, United Kingdom, +44 (0)115 941 5401

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