Insights from Sygnature Discovery about protein supply, structure determination, mass spectrometry, and biophysical characterisation.
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Working collaboratively to provide creative solutions to protein  challenges in drug discovery

Membrane Proteins: One of Our Defining Strengths

Our membrane protein specialists are a key differentiator within Sygnature’s Protein Science group. Their expertise in tackling complex drug targets is a key reason partners choose to work with us.
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Membrane

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Why Membrane Proteins Matter 

Membrane proteins are essential to cellular function and represent over 60% of drug targets, yet they remain notoriously difficult to work with.This article explores the challenges and how our team is solving them.

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Why Everyone's Talking about Metabolic GPCRs

Discover why metabolic GPCRs are at the forefront of metabolic disease drug discovery programs and how cryo-EM and structure-based design are driving multi-target drug development.

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Meet Margeoux

We’re thrilled to introduce Margeoux, one of our talented membrane protein scientists who recently made the leap from academic research to industry. Learn about her journey, her role, and what excites her most about working at Sygnature.
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We're Continuing to Grow

We’re excited to welcome several talented scientists to the Protein Science group. Their diverse expertise strengthens our capabilities and reflects our ongoing commitment to scientific excellence and innovation.
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SD Icon_Dark Blue_Protein Expression & Purification

Protein Expression and Protein Purification

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SD Icon_Dark Blue_Structural Biology

Protein Structure Determination

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SD Icon_Dark Blue_Biophysical Analysis

Protein

Characterisation

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Sygnature Discovery, BioCity, Pennyfoot Street, Nottingham, Nottinghamshire NG1 1GR, United Kingdom, +44 (0)115 941 5401

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